The difference between esophagitis and esophagoma includes the difference in clinical manifestations and pathological examination. Esophagitis is a flat lesion, which is benign and mainly manifests as heartburn, dysphagia, painful swallowing and retrosternal pain, etc. Those with combined vascular rupture may have vomiting blood or black stool, and pathological biopsy suggests inflammatory changes. Esophageal tumor is a lesion protruding from the lumen of the tube, which can be divided into benign tumor and malignant tumor. The differentiation between benign and malignant mainly depends on pathological analysis. Malignant tumors include squamous carcinoma, lymphoma, smooth muscle sarcoma, etc. The main manifestation is progressive dysphagia, which can also have chest pain and bleeding, and in later stages, wasting, anemia and distant metastasis. In addition, esophagitis can be transformed into esophageal cancer.