What are the commonly used embolic agents for hepatocellular carcinoma intervention? What are their advantages and disadvantages? The commonly used embolic agents are iodine oil, gelatin sponge, and steel ring; gelatin sponge and steel ring can permanently embolize the vessel, and iodine oil can be recanalized due to blood flow impact. Why should intervention be combined with other methods? Interventional treatment is a local treatment. Tumor, especially primary liver cancer, is a systemic disease, and interventional treatment alone cannot control the growth of potential lesions. Meng Yongbin, Department of Traditional Chinese Medicine and Oncology, Shanghai Changhai Hospital Interventional combined with radiofrequency for liver cancer, which liver cancer treatment can be used? Interventional combined radiofrequency for liver cancer is suitable for those with large tumors, poor iodine oil deposition or with tumor invasion in portal vessels or with metastasis in situ. Should we do intervention first and then radiofrequency and cryopreservation, or radiofrequency and cryopreservation first and then intervention? Can they be done at the same time? The general order is as follows: intervention first, then radiofrequency, freezing, and vice versa because the tumor vascular bed is destroyed causing intervention without target vessel super-selection.