Leg pain the next day after leg cramps at night can be relieved by the following methods: first, take warmth measures for the legs to avoid cold, moisture and overexertion of the leg muscles, and reduce the adverse stimulation of external environmental factors; second, conduct serum ion examination to determine whether there is a serious deficiency of calcium and potassium ions, and promptly supplement calcium and potassium preparations to restore the blood calcium and potassium concentrations to normal levels; third, massage the calf muscles gently and apply local heat to promote muscle blood circulation, which can quickly relieve the symptoms of leg muscle pain; fourth, take oral non-steroidal anti-inflammatory and pain-relieving drugs such as Third, the calf muscle for gentle massage and local hot compress, to promote muscle blood circulation, so that tension muscle fully relaxed, can quickly relieve leg muscle pain symptoms; fourth, can take oral non-steroidal anti-inflammatory, analgesic drugs, such as ibuprofen extended-release capsules, loxoprofen sodium, to promote the muscle inflammatory response to subside, to relieve leg muscle pain symptoms.