The common causes of thigh pain above the knee are as follows: First, thigh muscle strain, such as quadriceps muscle strain, patients with excessive exercise or excessive weight-bearing, can cause severe strain of quadriceps muscle in front of the thigh, there will be pain in front of the thigh symptoms, patients with knee joint activity will be weakened. Second, osteoarthritis of hip joint or necrosis of femoral head can cause radiating pain symptoms in front of thigh, accompanied by limited hip joint activities and hip joint pain, through X-ray examination, MRI examination, can find out the disease of the hip joint and the severity of the disease, and positive early diagnosis and early treatment can make the thigh pain symptoms above the knee joint be completely relieved, and the patient’s quality of life will be improved, in normal life, should be protected and protected. The patient’s quality of life will also be improved. In normal life, attention should be paid to the protection of thigh muscles and joints to avoid lesions and injuries. Bone tumor of distal femur, usually occurring in adolescents, if there is unexplained pain, and there is no obvious cause, should consult the doctor in time, through X-ray, CT or nuclear magnetic diagnosis or exclusion.