The difference between migraine and neuropathic headache lies in aspects such as pathogenesis and treatment. 1. Current research suggests that migraine is mostly related to heredity and other factors. The pathogenesis of neural headache is mainly due to muscle contraction and insufficient blood supply. 2. Migraine headache is mostly characterized by moderate to severe throbbing headache, and the site is mostly on one side or both sides. Neurogenic headache is mostly boring and heavy pain. The location is usually not fixed. 3. Migraine can choose dihydroergotamine, sumatriptan and other drugs; neurological headache can choose ibuprofen, celecoxib and other non-steroidal anti-inflammatory drugs. When headache discomfort, it is recommended to consult a doctor in a timely manner, under the guidance of the doctor to clarify the cause, reasonable treatment.