Many diabetic patients very much refuse to take oral hypoglycemic drugs, the reason is that “medicine is three points of poison”, take medicine will “hurt the liver” “kidney”. In fact, these views are one-sided and incorrect. First, the existing oral hypoglycemic drugs are strictly screened, with a long clinical application time, withstand the test of practice drugs. They are not ‘hepatotoxic’ or ‘nephrotoxic’ drugs. As long as the appropriate dose is used under the guidance of a doctor, it will not affect the liver and kidneys. Secondly, “medicine is three parts toxic” means that the majority of drugs are metabolized and discharged by the liver and kidneys, which can cause liver and kidney damage if not abused regularly. But under the guidance of a doctor is not this problem. Thirdly, does not taking medicine “protect” the liver and kidney? Not taking medication and letting blood sugar rise, high blood sugar is the biggest damage to the liver and kidneys. This practice is the same as not eating to protect your teeth or not walking to protect your joints, which is more than worth the loss in the end. Fourth, why do some patients really “liver and kidney eat bad”? That is long-term poor blood sugar control, high blood sugar to the liver and kidneys “bubble” bad, not eat drugs to eat bad. Fifth, what oral medication instructions have a lot of side effects? It is the responsibility and obligation of the instruction manual to provide a comprehensive description of the drug. The rare side effect of 1 in 10,000 should be mentioned and explained. It is as if any form of transportation has a certain rate of accidents, but this does not affect the convenience and speed that this brings. Compared to the benefits of taking the drug to lower sugar, these side effects are not worth causing undue concern. Sixth, is metformin really “toxic”? Like other drugs, metformin is a very safe glucose-lowering drugs, is the first choice of obese type 2 diabetic patients with drugs. Metformin “poisonous”, more laymen, not the views of doctors. Seventh, insulin is the safest? Insulin is only one of the glucose-lowering drugs, and is not superior to other drugs. As for what option to choose, it must be analyzed according to the specific situation of the patient. Insulin can never solve all the problems of diabetes.