Solid nodules of the breast with smooth margins and round-like masses can be followed up and observed regularly and are considered more likely to be benign and do not require surgical treatment for the time being. For solid nodules with irregular margins, burr or lobar changes, and mammography finding scattered clusters of calcifications around the lesion, and ultrasound suggesting that the nodule is rich in feeding vessels, this situation does not exclude the possibility of malignant nodules and should be surgically removed in a timely manner, under epidural anesthesia, with preoperative ultrasound localization, intraoperative frozen pathology, and if necessary, radical excision. The nodules are most commonly found in the breast. The most common cause of breast nodules is breast enlargement, which is associated with irregular glandular growth and painful symptoms.