Fibroids are one of the most common benign tumors of the female genitalia, mostly due to the influence of certain factors that can cause lumps to grow on the uterine wall. About 20% of women over the age of 30 have fibroids, and there are five groups of people who are most at risk and need special attention. The first group is those affected by genetic factors, as evidenced by racial differences and family aggregation. For example, the incidence of fibroids is 2 to 3 times higher in blacks than in whites or Asians, and 4.2 times higher in people whose immediate family members or sisters have had fibroids than in those without a family history of the disease. The second category is people who have factors that cause ovarian hyperfunction, for example, polycystic ovary syndrome; and diseases with ovarian endocrine function, such as granulosa cell tumor and ovarian granulosa cell tumor, which can lead to fibroids. The third category is related to the number of births, and the incidence of uterine fibroids is inversely proportional to the number of births. Nowadays, elderly people in their 70s have had at least four children in their lifetime, which explains why women rarely suffered from this disease in the past. This is because of the six-month period of pregnancy and breastfeeding, during which the ovaries do not ovulate and hormone secretion is at a low level, thus protecting the health of the uterus. The fourth category is influenced by the body type. Why eat the same food, or sisters suffer from the disease but not yourself, this is related to the individual’s constitution. Because hormone action requires receptors, some people have more sensitive receptors, easily affected by hormones, then relatively easy to suffer from uterine fibroids. The fifth category is related to life. The first is the obesity factor. Studies show that for every 10 kg increase in weight, the risk of fibroids increases by 21%, because an obese body is more likely to synthesize estrogen. In addition, exercise can reduce the prevalence of fibroids, according to statistics, non-athlete college students are 1.4 times more likely to develop fibroids than those who exercise regularly; women who smoke are also less likely to develop fibroids because cigarettes have substances that antagonize estrogen. In addition, Professor Chen Chunlin warned against abusing birth control pills, as overuse of the pill can increase estrogen in the body, which can easily lead to fibroids.