Patients with hypertension combined with asthma are generally not recommended to use beta-blockers. beta-blockers are one of the first-line antihypertensive drugs, and its representative drugs include metoprolol, bisoprolol, propranolol, atenolol, etc. These drugs can not only slow down the heart rate, lower blood pressure and prevent left ventricular remodeling, but also serve as secondary prevention drugs for angina pectoris and heart failure. However, if the patient has combined asthma or hypertension combined with chronic obstructive pulmonary disease, the use of such drugs is not recommended for such people because it may induce the aggravation of asthma symptoms and make the patient’s dyspnea appear more frequently. However, if hypertension is combined with asthma, drugs like calcium channel blockers, priligy, and sartans are available. Comparatively, bisoprolol and metoprolol are more highly selective beta-blockers, however, they are also not recommended for use in patients with asthma.