Children can get nephrotic syndrome, which may be caused by viral infection, drug factors, genetic factors and so on. 1. Viral infection: because children’s body resistance is weak, when they are infected by hepatitis B virus, hepatitis C virus and human papilloma virus, it will lead to sclerosis of glomeruli of focal segments, which will lead to Nephrotic Syndrome. 2. Drug infection: if children take antibiotics and non-steroidal anti-inflammatory drugs, such as cefixime and ibuprofen for a long time, it may lead to the damage of liver by the drug components, which may lead to nephrotic syndrome. 3. Genetic factors: If the parents of a child suffer from nephrotic syndrome, the child may inherit the genes of the parents, resulting in genetic defects that cause nephrotic syndrome. There may be other reasons for children to get nephrotic syndrome, it is recommended to go to the hospital in time, improve the examination to clarify the cause of the disease, and then give targeted treatment or therapy under the guidance of the doctor.