Sebaceous cysts, suddenly become large, red, swollen and painful, may be due to local infection, it is recommended to go to the hospital for a detailed examination, and then according to the specific conditions and doctor’s advice for treatment. If the tumors suddenly become large and red, swollen and painful, if the local also has obvious fluctuation, it proves that the symptoms of infection is more obvious, it is recommended to consider incision and drainage, the pus and necrotic tissues clean, and under the guidance of the doctor to take antibiotic medication, such as cefixime dispersible tablets, roxithromycin capsule and other medications, to be the inflammation subsides, and then surgical resection of the treatment. After the operation, we should pay more attention, do a good job of postoperative protection and care, to avoid causing secondary infection . Usually pay more attention, it is recommended to take more rest, avoid eating spicy and stimulating food in diet, be light and nutritious, avoid smoking and alcohol, and develop a good dietary habits, but also pay attention to the cleanliness of the surgical site, try to avoid too much contact with the surgical site, so as not to cause bacterial infections.