If there is no cold, fever, allergy, acute infectious disease, etc., simple total bilirubin 17.76 and indirect bilirubin 14.59 can be injected with hepatitis B vaccine. The normal range of total bilirubin is 1.7~17.1 μmol/L, and the normal range of indirect bilirubin is 1.7~13.7 μmol/L, which varies slightly with different monitoring instruments. Total bilirubin 17.76μmol/L and indirect bilirubin 14.59μmol/L are on the high side. Contraindications for hepatitis B vaccination mainly include colds, allergies, or acute infectious diseases, and the vaccination can be given after the disease is cured. Elevated bilirubin is not a contraindication to hepatitis B vaccination, but it is recommended to go to the hospital to find out the cause of elevated bilirubin. Elevated bilirubin is not a contraindication to hepatitis B vaccination, and the hepatitis B vaccine does not raise bilirubin levels. For patients with high bilirubin, it is recommended to visit the hospital to find out the cause of the elevated bilirubin, and to consult with a specialist to see if hepatitis B vaccination is allowed.