The statement of the most obvious signs of liver cancer is slightly absolute. After suffering from liver cancer, there may be fever, loss of appetite, jaundice and other related clinical manifestations. Liver cancer is a malignant tumor of digestive system caused by hepatitis virus, heredity, alcohol and other factors, and there is no specific clinical manifestation in the early stage of the disease. With the development of the disease, systemic manifestations such as fatigue, fever, unexplained emaciation and other symptoms such as loss of appetite, pain in liver area, abdominal distension, jaundice, itchy skin and so on may appear. Sometimes liver cancer does not show obvious signs, therefore, when discomfort occurs, one should go to hospital for standardized diagnosis and treatment in time to avoid delaying the condition.