Multiple polyps of the colon with a diameter of 0.6cm can be surgically removed endoscopically. Colon polyps can be categorized into inflammatory polyps, hyperplastic polyps, adenomatous polyps and cancerous polyps. When the diameter of colon polyps is less than 5mm, they can be removed by endoscopic forceps and followed up regularly. If the polyps are large, endoscopic resection or endoscopic stripping is feasible. If the polyps are large and widely distributed, and cannot be removed cleanly under endoscopy, partial colectomy or total colectomy should be selected according to the patient’s physical condition and other conditions. Colon polyps are generally asymptomatic, if the patient has abdominal pain, diarrhea and other symptoms, you can choose antibiotics (such as norfloxacin), antidiarrheal drugs (such as montelukast) and other symptomatic treatment; if the patient has abdominal distension, constipation and other symptoms, the feasibility of soapy enema, gastrointestinal decompression and other treatments. The emergence of multiple polyps in the colon, it is recommended to timely visit the gastroenterology department, according to the patient’s condition under the guidance of the doctor to standardize the treatment, the drug should be used under the guidance of the doctor.