Taking Kidney and Brain Capsules together with methylcobalamin may produce adverse reactions such as metal poisoning. This is because Kidney and Brain Nourishing Capsule contains Cinnabar, which contains elemental mercury. The combination of methylcobalamin and mercury may lead to metal poisoning. Tonifying Kidney and Brain Capsules is mainly composed of antler velvet, ripened rhubarb, wolfberry, poria, cinnabar and other traditional Chinese medicines, due to the presence of cinnabar as a traditional Chinese medicinal herb, so when using it, we should pay attention to the relevant medicines at the same time, to avoid adverse reactions. Methylcobalamin is a kind of B vitamin, so workers engaged in mercury and its compounds should not take a large amount of methylcobalamin orally for a long time. While taking methylcobalamin, also try to avoid taking it at the same time with drugs containing mercury to avoid adverse reactions of metal poisoning. Because cinnabar contains mercury, taking Kidney Tonic Capsules together with methylcobalamin may produce adverse reactions such as metal poisoning. In short, tonifying the kidney and brain capsule and methylcobalamin is generally not recommended to take together, the use of specific drugs, generally need to follow the doctor’s instructions.