Pain in the middle of the foot may be caused by plantar fasciitis, ankle-tube syndrome, lumbar disc herniation and other reasons. 1. Standing for a long time or wearing hard-soled shoes or walking for a long time may lead to soft tissue injuries such as plantar fascia ligaments, causing plantar fasciitis. Most patients have a history of long-term walking as well as long-term standing, which can be relieved by rest, physical therapy, massage and other treatments. 2. Ankle tube syndrome may cause tibial nerve compression, resulting in pain and numbness in the foot and toes. 3. Some patients with lumbar disc herniation may experience sciatica when the herniated disc compresses the nerve root, and some patients may also experience pain and numbness in the soles of the feet. If there is pain in the middle of the ball of the foot, it is recommended to go to the hospital for diagnosis in time.