Meningitis A+C vaccine is generally referred to as group A group C meningococcal polysaccharide vaccine, and adverse reactions include fever and pressure pain. The drug is recommended to be contraindicated in patients with epilepsy, convulsions, and other disorders. Group A group C meningococcal polysaccharide vaccine is mainly used for the prevention of epidemic cerebrospinal meningitis caused by group A and C meningococcal infection. Some patients may have transient fever after receiving group A and C meningococcal polysaccharide vaccine, and a small number of patients may have pressure pain at the injection site. Avoid vaccination with Meningococcal Polysaccharide Vaccine Group A-C if the patient has epilepsy, convulsions, fever, acute infectious disease, renal disease, cardiac disease, or active tuberculosis. In general, patients need to be observed at the vaccination site for 30 minutes before leaving after receiving group A group C meningococcal polysaccharide vaccine to prevent adverse drug reactions. In addition, patients who experience serious adverse reactions after receiving group A group C meningococcal polysaccharide vaccine need to seek prompt medical attention and follow the doctor’s instructions.