Hepatocellular hepatocellular carcinoma is the most common type of primary liver cancer. Patients with chronic liver disease present with persistent liver inflammation, liver fibrosis and abnormal regeneration of hepatocytes. These abnormal physiologic processes can lead to cirrhosis and to a series of genetic and epigenetic events that culminate in the formation of abnormal proliferative nodules. Hepatocellular carcinoma (HCC) is the main pathological type of primary liver cancer, which can account for 85% to 90% of cases.The occurrence and progression of HCC are closely associated with HBV infection, HCV infection, chronic alcohol abuse, metabolism-related fatty liver disease, consumption of aflatoxin-contaminated food, schistosomiasis, and family history of liver cancer. Hepatocellular carcinoma treatment includes radical treatment (surgical resection, liver transplantation, ablation therapy), systemic therapy (targeted therapy, immunotherapy), supportive therapy and palliative therapy. Patients are advised to visit regular hospitals to avoid delay in diagnosis and treatment.