Some women have asked whether and how they need to be treated for the inflammatory reaction of the cervix found on examination. I feel this is a good question and would like to share my opinion here. Indeed, many women are found to have cervical smear reactive inflammatory cell changes on physical examination, while they do not have signs of inflammation themselves, such as scratching, increased leucorrhea, abnormal odor, etc. Does this condition require treatment? First, we should understand the composition of the leukorrhea. The components of leukorrhea include: secretion from vaginal epithelium, which is the main substance that keeps the vagina moist; secretion from cervical glands and endometrium, which is small in amount and its nature changes with different stages of menstrual cycle; exfoliated cells from vaginal epithelium and white blood cells; secretion from sebaceous glands of labia minora; secretion from vestibular gland, etc. Secondly, we should understand the form of reporting the results of the liquid-based thin film examination. In the column of reactive inflammatory cell changes, there are four items: “inflammatory reaction, severe, moderate, mild, none”, and depending on the number or ratio of leukocytes and lymphocytes, the doctor will check one of “severe, moderate, mild, none”. Since leukocytes are one of the components of normal leukorrhea, all cervical fluid-based smears will have leukocytes and will report different responses to inflammation, either severe or moderate or mild. In other words, almost no woman will receive a report of no “reactive inflammation”, even if she is a very healthy person. At least in my own work, I have never seen a “reactive inflammation, none” report on a liquid-based thin film. With that said, it is clear that a “reactive inflammatory cell change” on a basal slide does not require treatment, and it is not right to use anti-inflammatory drugs, whether they are recommended by a doctor or used by the woman herself. The role of white blood cells is to stand guard for us, to fight for us when disease-causing organisms invade. We need them, not to expel them! What we need to expel are disease-causing microorganisms such as bacteria (which cause bacterial vaginitis), mycobacteria (which cause mycotic vaginitis), trichomonas (which cause trichomonas vaginitis), etc. If there are manifestations of vaginal inflammation such as itching, increased leucorrhea, abnormal odor, etc., and examination reveals bacteria, mycobacteria or trichomonas, it is time to treat them with anti-bacterial, anti-mycotic or anti-trichomonas drugs depending on the causative organism, rather than treating “reactive inflammatory cell changes”.