Scleroderma granulosa is a thickening of the skin with patches of dilated capillaries and subcutaneous calcifications, commonly found on the fingers, face, lips, tongue and forearms, with the most common site being the tips of the fingers. Scleroderma is an inflammatory deformational change of the skin that often causes multisystem damage. Including the digestive tract, lungs, heart and kidneys, but the skin lesions are the most common. 1. Early skin lesions: in the early stage of scleroderma, the skin shows mild erythema, which can be erythematous, itchy, or edematous, and the skin changes can spread to the forearms and forearms and other parts of the chest, but often stops at the front of the upper limbs. Diffuse scleroderma, extensive hardening of the skin with deepening or hypopigmentation. 2. Skin progression lesions: as the disease progresses, the normal wrinkles and folds on the skin surface disappear, the skin is shiny and taut, and the facial skin becomes thin, which is characterized by dullness and expressionlessness. Fingers, lips, face and other parts of the patchy capillary dilatation and subcutaneous calcification, which manifests itself in the form of small spots or large clusters of varying sizes covering the distribution of the knees, elbows and other prominent parts. 3. Skin sclerosis stage lesions: skin thickening is more obvious, often itchy skin, progressive development, until the inflammation and fibrosis stops, the fibro-hardened tissues will be tightly adhered to the subcutaneous tissue so that the skin thinning, the formation of seemingly granular changes. Scleroderma should be diagnosed and treated early, and attention should be paid to smoking cessation, avoiding exposure to cold, and keeping the whole body warm. If you have symptoms of scleroderma-related skin changes, you should go to the rheumatology and immunology department of the hospital in a timely manner, under the guidance of the doctor to carry out the relevant diagnosis and treatment, so as to avoid delays in the condition.