According to Chinese medicine practitioners, when regulating constipation caused by coldness in the spleen and stomach, medicines with the effect of warming the middle and strengthening the spleen can be chosen, such as Radix Rehmanniae Pills with Radix Rehmanniae Ziziphi. The medicine is composed of Radix Polygoni Multiflori, Radix Codonopsis Pilosulae, Rhizoma Atractylodis Macrocephalae, Radix et Rhizoma Atractylodis Macrocephalae, Radix et Rhizoma Glycyrrhizae Praeparatae, and so on, which has the effect of warming the center and strengthening the spleen, and it can be used for the treatment of epigastric and abdominal coldness and pain (the stomach, epigastric and abdominal areas feel cold and painful), and cold limbs and loose stools (the feces are thin and not shapely) and other diseases. It should be noted that the drug is not suitable for people with acute gastroenteritis and anal burning. It should also be used with caution in pregnant women. Patients with constipation caused by coldness in the spleen and stomach are advised to go to regular hospitals for treatment under the guidance of professional physicians.