Hand numbness when lying down and standing up may be related to arm compression, or it may be caused by cervical spondylosis, thoracic outlet syndrome and other reasons. 1. Arm pressure: when lying down, if the arm is under pressure for a long time, resulting in poor blood circulation in the arm on the pressure side, it will cause hand numbness, and after standing up the arm pressure symptoms can be lifted, and hand numbness symptoms will disappear soon. 2. Cervical spondylosis: especially in the presence of cervical disc herniation patients, in the sleep due to the pillow height is not appropriate or improper sleeping posture, resulting in local nerve root compression, will cause hand numbness. When you stand up, it will help to relieve the pressure on the nerve roots, which will relieve the symptoms of hand numbness. 3. Thoracic outlet syndrome: may be related to congenital developmental defects, trauma, poor posture and other factors, may often occur at night, lying down the hand numbness and pain symptoms, after getting up and moving, the symptoms may be reduced. Lying down, hand numbness standing up, may be caused by other reasons, if the symptoms recur, should be taken seriously, as soon as possible to seek medical attention, diagnosed, by the doctor’s guidance for treatment.