The danger of low HDL is an increased risk of cardiovascular diseases such as stroke and coronary heart disease. Low HDL reduces the ability to transport cholesterol and may lead to an increase in plasma cholesterol. This accelerates the process of atherosclerosis and increases the risk of cardiovascular diseases. The higher the HDL, the better, as it is a protective factor against cardiovascular disease, and ApoA1 can transport cholesterol from atherosclerotic plaques to the liver for further breakdown and utilization, thus preventing the onset and progression of atherosclerotic plaques. People with low HDL cholesterol and high risk factors for cardiovascular disease can take oral statins to raise HDL cholesterol, such as pravastatin and atorvastatin. In addition, people with low HDL should take medication as prescribed by their doctor. In addition to oral medications, lifestyle modifications should be observed and HDL levels should be monitored at all times.