Proctitis due to gonorrhea is usually treated by cephalosporin antibiotics. Proctitis due to gonorrhea is mainly caused by Neisseria gonorrhea infection. Treatment is mainly based on cephalosporin antibiotics, such as ceftriaxone sodium, which is given by intramuscular injection or intravenously. The common adverse reaction is allergic reaction, which is prohibited for those who are allergic to the drug. If you are allergic to cephalosporins, you can choose antibiotics such as macrolide for treatment. Gonorrhea-induced proctitis should be treated promptly, and all medications need to be used under professional medical supervision.