Thickening of mucosa of posterior wall of nasopharyngeal parietal is related to local stimulation of infection, allergy, physicochemical factor stimulation and other tissue hyperplasia. Clinical causes of the corresponding conditions mainly include acute inflammation of nasopharyngitis, reflux pharyngitis adenoid hypertrophy, tumor, and so on. 1. Acute inflammation of nasopharyngitis: the posterior wall of nasopharyngeal apex can have the manifestation of mucous membrane thickening by direct bacterial or viral infection, and it can also have this sign by the influence of inflammation of surrounding tissues and organs. Mainly for some lymphatic tissue, acute infection will appear mucosal edema, lymphatic tissue hyperplasia, caused by the thickening of the condition, the inflammation can be gradually improved after control. 2. Adenoid hypertrophy of reflux pharyngitis: after the reflux of gastric reflux to nasopharyngeal burning stimulation, it can cause mucosal thickening and dryness or increased mucus secretion symptoms belong to the pharyngeal tonsil enlargement, and chronic inflammatory stimulation has relevance, mainly triggered by recurrent upper respiratory tract infections. 3. Tumor: the most common one is nasopharyngeal carcinoma, with the proliferation of tumor cells, it will also lead to the thickening of mucous membrane of the posterior wall of the parietal of nasopharynx. When mucosal thickening occurs in the posterior wall of nasopharyngeal parietal, it is necessary to observe it through rhinoscopy when necessary, and the soft tissue lesions can be taken to do pathology to confirm the diagnosis of the condition, and then standardized treatment can be carried out under the guidance of clinical specialists after a clear diagnosis.