Central target-controlled analgesia, also known as programmable morphine pump technique, is one of the most advanced methods in the international pain community in recent years for the treatment of cancer pain and chronic intractable pain such as central pain and postherpetic neuralgia. The procedure: that is, under the guidance of C-arm X-ray fluoroscope, a special catheter is punctured through the lumbar space and placed in the subarachnoid space, then a morphine pump is implanted under the patient’s skin, and the catheter is connected to the pump by means of subcutaneous tunneling. The pump has a drug reservoir to store morphine solution, and the infusion system of the pump can continuously and slowly inject the drug into the cerebrospinal fluid in the subarachnoid space at a uniform rate through the catheter. Features: 1. This method can directly apply a small amount of morphine to the spinal cord and brain, avoiding the systemic toxic side effects caused by large amounts of oral medication. Because morphine acts directly on the endorphin receptors in the spinal cord and brain, so a small amount of morphine can achieve satisfactory analgesic effect and reduce the side effects brought by the systemic use of morphine, and the dose of applied morphine is only 1/300 of the dose needed for oral use. e.g.: 300mg of morphine is taken orally to achieve the same analgesic effect, and only 1mg of morphine is needed to act directly in the center. Intrathecal morphine – oral morphine, the comparison of the route of medication.2.Quick-acting pain relief, and can be prepared for different conditions of patients, different pain patterns, the corresponding procedures, targeted drug delivery, to provide personalized services, to achieve satisfactory analgesic effect.3.Automatic administration of drugs according to the daily set program, to avoid the tedious oral drugs on time.4.Help restore body functions, improve the quality of life. 5.Surgery is less traumatic and safe. 6.The system is all implanted in the body, no external ducts, avoiding infection, not affecting normal life, and can be bathed. 7.After a dosing, it can be used up to half a year before the medication needs to be changed, facilitating long-term pain control. Advantages: safe, less traumatic, significant efficacy, can significantly improve the quality of life, simple operation, good patient tolerance, less complications, suitable for all patients with cancer pain and chronic intractable pain who are not treated by other traditional treatment methods and drugs, or cannot tolerate the side effects of drug treatment, with high success rate. The treatment of various types of intractable pain by central target-controlled analgesia has been carried out overseas for a long time and has achieved very good clinical results.