Blood tests 1. Routine blood tests: to check for abnormal indicators, to indicate changes in the disease and to monitor adverse drug reactions. 2.Liver and kidney function: to check the function of liver and kidney, suggesting disease changes as well as whether the drugs are damaging the internal organs. 3, erythrocyte sedimentation rate (ESR): referred to as sedimentation, normal reference value: adult male 0-15 mm/h, female 0-20 mm/h. High sedimentation, excluding other causes, indicates that the disease is still active, the higher the more serious. A decrease in blood sedimentation indicates that the disease is under control. In rheumatic immune diseases, ESR higher than 25 mm/h is meaningful. 4.C-reactive protein (CRP): High CRP indicates the presence of infection, trauma and inflammation in the body, and the disease is still in the active stage. 5.Anti-streptococcal hemolysin “0” (AS 0): positive indicates the body harboring hemolytic streptococci, which can lead to rheumatic fever. 6, rheumatoid factor (RF): RF is common in a variety of rheumatic diseases and acute and chronic inflammatory diseases. Therefore, you can not rely on RF positive alone that you are rheumatoid arthritis. However, if the RF titer is high, multiple positive determinations, multiple positive methods, then the likelihood of rheumatoid arthritis is higher. 7, anti-cyclic citrullinated peptide antibody (CCP), anti-keratin antibody (AKA), anti-perinuclear factor (APF), anti-mutant citrullinated waveform protein (MCV), common in rheumatoid arthritis patients, especially for the diagnosis of early rheumatoid arthritis patients, as well as to determine the prognosis of the disease is of great significance. 8.Anti-nuclear antibody (ANA): Positive test is common in many diseases. A positive ANA in high titers is highly suspicious of SLE. Negative can almost certainly exclude the diagnosis of lupus. 9. Anti-ds-DNA antibody: seen almost exclusively in patients with SLE. And it is closely associated with active lupus nephritis. The higher the antibody titer, the higher the disease activity. 10. Anti-Sm antibody: almost only seen in patients with SLE. It is a marker antibody for SLE. However, not all patients with lupus show positivity. 11.Anti-SSA antibody and anti-SSB antibody: seen in many diseases, but have greater significance for the diagnosis of dry syndrome. 12.HLA-B27: It is a genetic test and has significance for the diagnosis of ankylosing spondylitis. Imaging tests 1.X-ray examination: usually choose the most serious part of the symptoms. If local symptoms are atypical, the doctor will choose the common site of disease attack for the film according to the identified direction of consideration. For example, in rheumatoid arthritis, the hands and wrists are often selected, and in ankylosing spondylitis, the bilateral sacroiliac joints and hip joints are often selected. Regular X-ray examinations allow for before-and-after comparisons to determine the effectiveness of treatment. 2, CT examination: higher resolution, conducive to the early detection of the disease, can be found in the X-ray can not show the lesion. It is of great significance to the diagnosis of the disease. 3.Magnetic resonance imaging (MRI) and ultrasound: it can show the internal lesions of the joints such as cartilage, synovium and joint effusion clearly, which is important for the early diagnosis of the disease and judgment of the condition.