Obesity is generally due to the imbalance of energy metabolism, calorie intake is more than the calorie consumption so that fat synthesis increases is the material basis of obesity. Treatment of obesity is based on dietary control and increased physical activity, supplemented by medication when necessary, and surgery for some patients. The principle of diet therapy is to limit the total daily calorie intake, so that it is lower than the amount of consumption. Exercise therapy, like diet therapy, is also the basic treatment for obesity. The more important aspect of exercise therapy is the consolidation and maintenance of weight loss. Exercise alone is often unsuccessful in weight loss. When diet and exercise therapy fail, medications may be used as part of a comprehensive weight loss program. Diet and exercise therapy should be tried for at least 2 to 4 weeks before medication is used. For some patients with obesity or obesity-related diseases, repeated failure of other treatments, surgery can be considered under certain conditions. Obese patients can be under the guidance of specialized physicians to reduce weight, so as not to lead to adverse consequences.