Thyroid puncture is not necessarily cancerous. Thyroid puncture is only a means of examination, and pathologic examination can be performed by puncture to clarify the benign or malignant nature of thyroid nodules of category 4 and above. Puncture of the thyroid gland is only used to determine the benign or malignant nature of localized lesions, and the appropriate treatment plan is carried out according to the results of the puncture. Fine needle aspiration biopsy of the thyroid gland is highly accurate and highly suggestive of nodular thyroid disease. It is usually guided by ultrasound and puncture of suspicious nodules in the thyroid gland, which is sent to the Department of Pathology for analysis and other examinations, and then clinicians will make a comprehensive assessment to determine the benign or malignant nature of the nodules. Thyroid puncture is only a means of examination, in order to clarify the diagnosis. Patients need to actively cooperate with the doctor for active treatment, keep a calm mind, do not overstress, and follow the doctor’s instructions to avoid further development of the disease.