Under normal conditions, the intracellular and extracellular calcium ion concentrations are kept in dynamic balance. Modern medical research has found that when intracellular calcium ion concentration continues to increase, causing cellular excitation-contraction decoupling, it will lead to hypertension, myocardial infarction, heart failure, sudden death and other diseases, recently called intracellular “calcium deposition” or “calcium in-flow This is recently called intracellular “calcium deposition” or “calcium in-flow”. Calcium deposition is a disease in which insoluble calcium salts are deposited in the tissues. They are classified as idiopathic, metastatic, and dystrophic. Idiopathic calcium deposits are mostly of unknown origin, and metastatic calcium deposits are secondary to disorders of calcium and phosphorus metabolism, such as hyperparathyroidism, multiple myeloma, and phosphate retention due to renal insufficiency. Dystrophic calcium deposits are most often secondary to skin or tissue injury. Most patients have idiopathic or secondary to local tissue injury; a few are familial and metabolic. Examples include hypercalcemia and hyperphosphatemia, vitamin D toxicity, diabetic renal dialysis, concomitant connective tissue disease, and other crystalline deposition disorders. Most people with calcified deposits in tendons can be asymptomatic with a histologically concentrated granular or cheese-like material. Severe pain occurs only when the deposits increase in size and compression or trauma and the bursa ruptures, causing inflammation. Inflammatory adhesions of the bursa from calcified deposits may also be present, causing pain, limitation of movement, and systemic symptoms.