Beta-blocker representative drugs such as metoprolol succinate and bisoprolol, as a common drug in cardiology, are widely used in patients with hypertension, coronary artery disease, myocardial infarction, arrhythmia and heart failure. Since β-blockers can significantly relieve angina and improve the ischemic state of patients, they are especially suitable for patients with hypertension combined with heart attack and hypertension combined with angina pectoris. Young hypertensive patients usually show symptoms of increased sympathetic activity ~ rapid heart rate. Beta blockers can effectively inhibit excessive sympathetic activation and slow down the heart rate to exert antihypertensive effects. Heart rate control is an important aspect of the treatment process for patients with hypertension. Studies have shown that increased heart rate (resting heart rate >80 beats/min) is a cardiovascular risk factor for hypertensive patients. Domestic and international guidelines and a large amount of evidence-based evidence show that patients with a resting heart rate of <70 beats/min have a better prognosis. β-blockers slow down the heart rate and reduce myocardial oxygen consumption by blocking the heart's β receptors. In myocardial infarction, the heart rate should be controlled at 55-65 beats/min by slowing down the heart rate and reducing myocardial oxygen consumption to relieve angina pectoris. Patients with chronic heart failure taking beta-blockers can have significant improvement in cardiac function. Certain arrhythmias such as sympathetic storms are more uniquely and significantly effective with beta-blockers, reducing the risk of sudden death and improving prognosis. However, it should not be used when there is an acute asthma attack; when there is significant conduction block. As a prescription drug, it needs to be taken under the guidance of a regular hospital doctor and pharmacist.