According to clinical data, the incidence of gallstones in China has gradually increased in recent years. Many patients often fail to detect the disease in the early stage of gallstones, which eventually leads to the deterioration of the disease. Understanding the early symptoms of gallstones is very meaningful for the treatment of the disease. What are the clinical symptoms of gallstones? 1. Gallbladder stones usually have no obvious symptoms in the early stage, and most of them are found during routine physical examination. Sometimes they can be accompanied by mild discomfort and are mistaken for gastric disease without timely consultation. 2.Some single or multiple gallbladder stones exist freely in the gallbladder, which are not easily embedded and rarely produce symptoms, and are called asymptomatic gallbladder stones. 3.Small stones in the gallbladder can be embedded in the neck of the gallbladder, causing clinical symptoms, especially when the gallbladder contracts after eating a fatty diet, or due to the change of body position during sleep, the symptoms can be exacerbated. 4.When the gallstone is embedded in the neck of gallbladder, it causes acute obstruction, resulting in increased pressure in the gallbladder, and bile cannot be discharged through the neck of gallbladder and gallbladder duct, which causes clinical symptoms, usually manifested as biliary colic. It presents as a persistent right upper abdominal pain with paroxysmal intensification, which can radiate to the right shoulder and back, and is often accompanied by nausea and vomiting. In some patients, the clinical symptoms can be relieved by themselves after a few hours. 5. If the gallbladder stone is not relieved, the gallbladder will continue to increase in size and even become infected, thus progressing to acute cholecystitis. If the treatment is not timely, a small number of patients can progress to acute purulent cholecystitis, and in severe cases, gallbladder perforation can occur, with serious clinical consequences. Patients with gallstones should undergo surgical treatment as soon as their symptoms worsen, taking into account their own situation. At the same time, patients with gallstones should pay special attention to limit the intake of cholesterol, avoid eating foods containing high cholesterol, such as animal heart, liver, brain, intestines, as well as egg yolk, turkey eggs, caviar and chocolate.