The vertical groove from fontanel to forehead may be a bone gap, which is normal. However, some infants have a calcium deficiency, which is not normal. In newborn babies, a vertical groove on the forehead may occur because the bones of the skull have not yet closed. If the infant is not accompanied by other uncomfortable symptoms and the head circumference is normal, it is considered normal and parents do not need to worry too much, and the vertical groove between the forehead can gradually close and disappear with time. The vertical grooves between the foreheads will gradually close over time. Daily attention should be paid to the care of the infant’s head, avoiding external impacts and nutritional intake. The vertical groove from fontanel to forehead in some infants is caused by calcium deficiency, which is abnormal and easily accompanied by symptoms such as inattention and cramps. Diagnosis is usually aided by micronutrient tests and other tests such as CT of the brain. For children with a clear calcium deficiency, calcium can be supplemented with food and, if necessary, calcium supplements as prescribed by the doctor. Infants with a vertical groove from fontanel to forehead need to be examined by a doctor to clarify the specific situation and take appropriate treatment measures.