Lateral knee pain may be caused by soft tissue injury, osteoarthritis of the knee, traumatic fracture and other factors. 1. Soft tissue injury: mainly meniscus and medial and lateral collateral ligaments and other soft tissue injuries, the patient may be due to strenuous exercise or long-term weight-bearing activities caused by meniscus or collateral ligament injuries, thus causing lateral knee pain. 2. Osteoarthritis of the knee joint: it is caused by degenerative changes of the knee joint. Degenerative changes in the knee joint will lead to osteophytes, decreased stability of the knee joint, causing increased wear and tear of the joint, resulting in lateral knee pain. 3. Traumatic fracture: if the patient has a history of trauma to the side of the knee, such as impact, resulting in knee tibial plateau or femoral condyle fracture, resulting in lateral knee pain. Lateral knee pain is also related to many factors, patients should go to the hospital in time to identify the cause of the disease and receive appropriate treatment.