Acne on the face at present there is no rub what medicine is the most effective statement, you can rub benzoyl peroxide, nonanoic acid, antibiotic drugs, the specific efficacy of individual differences. 1. Benzoyl peroxide: one of the topical antibacterial drugs of choice for inflammatory acne, peroxide can slowly release new ecological oxygen and benzoic acid after topical application, which can kill Propionibacterium acnes and dissolve acne. 2. Nonanedioic acid: it can be formulated into 15%~20% cream for external use, which can reduce the surface of facial skin, hair follicles and sebaceous glands flora, inhibit Propionibacterium acnes, and have a dissolving effect on acne. 3. Antibiotics: moderate to severe acne patients need to use antibiotic treatment, commonly used drugs are erythromycin, clindamycin, fusidic acid cream and so on. After acne, it is recommended that patients need to consult a doctor in time and use medication under the guidance of the doctor.