Myocardial ischemia caused by left ventricular diastolic dysfunction can be treated with drugs such as isosorbide nitrate, metoprolol or diltiazem. 1. Isosorbide nitrate: nitrate drugs can not only reduce myocardial oxygen consumption, so that myocardial cells are less susceptible to ischemia, but also dilate the coronary arteries for myocardial blood supply, so that myocardial blood supply is more adequate. In addition, nitrate drugs can also reduce left ventricular filling pressure, improve left ventricular compliance to improve its diastolic function. 2. Metoprolol: In addition to reducing myocardial oxygen consumption and improving myocardial blood supply, metoprolol can also reduce myocardial contractility, slow heart rate, prolong ventricular diastolic period and improve left ventricular diastolic function. 3. Diltiazem: The effect of dilating coronary arteries is stronger, but patients with heart failure need to be used with caution. If you need to use the drug, it is recommended to use the drug under the guidance of a doctor, not blindly self-medication to avoid adverse effects.