High free thyroxine after total thyroidectomy may be related to overdose of postoperative replacement medication, and professional physicians can be consulted to adjust the medication. After total thyroidectomy, there will be different degrees of hypothyroidism, and then need to take levothyroxine sodium tablets and other drugs to replace the treatment. If the oral dose of levothyroxine sodium tablets and other drugs is too large, it may cause high free thyroxine, then you need to consult a doctor to adjust the dosage of medication, the specific use of medication needs to be directed by a doctor. Thyroid function needs to be monitored regularly after total thyroidectomy, and if abnormal thyroid hormone levels are found, consultation and treatment should be carried out under the guidance of specialized physicians.