There are many factors that can cause cold knees, and the treatment should be chosen according to the different causes of the disease. The causes include localized cold, knee arthritis, rheumatoid arthritis, and so on. Specific treatments include physical therapy, medication, and surgery. 1. Localized cold: Sitting for a long time and blowing cold air can trigger localized cold. In this case, adequate rest, pay attention to warmth will be relieved, but also can be hot compresses to accelerate local blood circulation, accelerate the treatment. 2. Knee arthritis: Knee arthritis will also appear knee cold symptoms, first of all, patients can take non-steroidal anti-inflammatory drugs such as ibuprofen to relieve pain, control inflammation. If the effect is not good, you can inject glucocorticoids and other drugs into the joint cavity to reduce inflammation. In severe cases, surgical treatment can be performed, such as artificial knee replacement. 3. Rheumatoid arthritis: patients can take non-steroidal anti-inflammatory drugs such as celecoxib to reduce inflammation and pain, while taking drugs to control rheumatoid rheumatoid such as tretinoin and leflunomide to control the progression of rheumatoid rheumatoid. Other causes of cold knees include gout and arterial embolism. Therefore, it is recommended that patients with cold knees should consult a doctor in a timely manner and be treated according to the specific situation.