Callus in medicine refers to callus, which has a certain role in protecting the organism, generally without treatment. If the corns are too thick, affecting the normal life, you can take general treatment, medication and other ways to remove. 1. General treatment: It is recommended that callus patients wear loose and comfortable shoes to avoid squeezing the foot. You can apply moisturizing cream on the soles of the feet to keep the skin moisturized. You can also use surgical blades to remove calluses under the guidance of doctors. 2. Medication: patients can follow the doctor’s instructions to use urea cream, which has the effect of promoting the hydration of the stratum corneum. You can also use salicylic acid ointment, retinoic acid ointment and other exfoliators, can soften the stratum corneum, exfoliation, but retinoic acid drugs have the risk of teratogenic. If the patient has a callus on the soles of the feet, it is recommended that you can go to the hospital, follow the doctor’s instructions for medication, not self-medication.