Chronic atrophic gastritis with celiac disease can be treated by general treatment, drugs or surgery. 1. General treatment: patients with chronic atrophic gastritis with celiac disease should pay attention to the diet should be kept light, easy to digest food, reduce the intake of stimulating food, chewing and swallowing to reduce the stimulation of the stomach. 2. medication: chronic atrophic gastritis with erosion and Helicobacter pylori infection has a certain relationship, usually can follow the doctor’s instructions to use medication, commonly used quadruple therapy, i.e., amoxicillin, clarithromycin, bismuth pectin, omeprazole used in combination to eradicate Helicobacter pylori. In addition, according to the patient’s condition, gastric mucosal protective agents such as aluminum magnesium carbonate can also be selected. 3. Surgery: The common surgical method is endoscopic submucosal dissection, which can completely remove the lesion and prevent the disease from deteriorating. If patients with chronic atrophic gastritis with erosion, it is recommended to go to the hospital in a timely manner, after a clear diagnosis, and actively cooperate with the doctor for treatment.