General anesthesia is mainly achieved through intravenous injection, intramuscular injection, respiratory inhalation, enema and other methods to make the drug into the body, so as to achieve the purpose of general anesthesia. The longer the duration of general anesthesia for surgery, the greater the side effects may be. Digestive symptoms, respiratory depression, allergies and other symptoms may occur. 1. Digestive system symptoms: patients may experience nausea and vomiting, which is often related to the metabolism of anesthetic drugs. Due to the long duration of general anesthesia, the body is unable to fully metabolize it for a while, leading to irritation of the digestive system and discomfort. 2. Respiratory inhibition: before the anesthetic agent metabolism is completed, the anesthetic agent will lead to slower respiration and smaller expiratory volume. With the prolongation of time, the drug is metabolized slowly and breathing can be fully restored. 3. Allergic reaction: Some patients have allergic reactions to the ingredients in the drug due to intolerance of the body. At this time there may be skin itching and hives and other phenomena. It is recommended that when the above symptoms occur, you should go to the hospital in time for examination and follow the doctor’s instructions for relevant treatment.