The mechanism of lowering plasma cholesterol of ezetimibe is mainly to inhibit the absorption of cholesterol. Ezetimibe attaches to the brush border of the villi of the small intestine and inhibits the absorption of cholesterol, thus decreasing the transfer of cholesterol from the small intestine to the liver, resulting in a decrease in hepatic cholesterol stores and thus an increase in blood cholesterol removal. It does not increase bile secretion or inhibit cholesterol synthesis in the liver. Indications: It is indicated for the treatment of primary hypercholesterolemia, pure familial cholesterolemia, phytosterolemia and so on. Ezetimibe can be used in combination with statins to inhibit both cholesterol absorption and synthesis and enhance the therapeutic effect of the drug. Adverse reactions: mainly include abnormal liver function, abdominal pain, diarrhea, abdominal distension, as well as nausea, acid reflux, cough and so on. Contraindications: patients with active liver disease, allergy to drug ingredients, pregnant women and lactating women. When choosing Ezetimibe for treatment, it is important to follow the doctor’s instructions strictly and not to use the drug without authorization.