Nerve block is the direct injection of drugs or physical stimulation into or near the nerve trunk, plexus, brain nerve or spinal nerve root, sympathetic ganglion and other nerve tissues to block the nerve conduction function. The purpose of nerve block is to relieve pain, improve blood circulation and treat painful diseases. It originated in the Soviet Union and the United Kingdom, and is also known as procaine closure therapy, which involves injecting procaine into the local pain points of the body to block the transmission of abnormal stimuli to the brain, thus changing the metabolism of the lesion and accelerating the healing of the disease. The term “Neural blockade” or “Nerve block” has been used worldwide for nearly 100 years and is still in use today, referring to the blocking of the conduction of nerve impulses by drugs and other means. In any case, it should not be translated as “closed” or “nerve block”. However, there are still many doctors who call “nerve block” or “injection therapy” as “closure”. The term “closure” was created in China in the 1950s, and it is understandable that it was difficult to understand the correct terminology abroad because of the difficulty in exchanging academic information with foreign countries. Over time, it was called a habit. But nowadays, it is better to advocate the use of correct international medical terminology. It’s like calling “abdominal pain” a “stomach ache”; although there is nothing wrong with it and everyone can understand it, it just comes out of a doctor’s mouth and makes people feel irregular. Many doctors who are not specialized in pain management, and even some nursing staff, due to lack of systematic knowledge and training, are keen to inject multiple drugs at pain points, acupuncture points or nerve endings to relieve pain, which they call themselves “closed therapy”. Some add small amounts of local anesthetic drugs to the injection solution, while others do not. Some doctors inject a wide variety of drugs locally, such as antibiotics, animal blood products, animal organ products, herbal preparations, anti-immune preparations, and anti-tumor drugs into the injection. Although this type of treatment can sometimes relieve the pain of some patients, many instances of complications and medical disputes have occurred. There are also some social loafers, to make money for the purpose of “a needle away”, everywhere “closed”, so that the word “closed” adds a bad color. This “closed therapy” name is widely circulated, so that some medical personnel and some patients on the regular “nerve block” also have misunderstanding, and even have fear. In my opinion, it is not appropriate for regular doctors to use the informal term “closed”. Moreover, the term “closure” is not found in the English, Russian, or Japanese pain literature, and it is better to refer to nerve blocks or injections in pain management, which are common worldwide and are scientific and standardized. As a result, the two concepts are completely unrelated, and they are two very different treatment methods. As for many ordinary people think that playing “closed” bones will become brittle, is this really the case? It may be that there are some half-educated people think that the drug contains hormones, containing hormones will be osteoporosis, I once found in a monograph on osteoporosis, such a sentence: “cortisone 25 mg given every other day, 1 year after the trabecular bone bone volume decreased by 3.5%. Of course, this does not mean that we can use hormones casually in pain treatment, but we should not be afraid to use hormones, but also fully understand the pharmacology and side effects of hormones, apply them reasonably, and prevent problems before they occur. The patients should gradually realize the difference between the two concepts and the two treatments. Especially with the continuous development of the pain industry, we should do more popularization of this field, so that the wrong view of mistaking “nerve block” for “closure” and even refusing to accept the treatment will definitely be clarified!