After middle and late stage colon cancer is treated by surgery and controlled by chemotherapy or radiotherapy after surgery, the 5-year survival rate is 60% to 70%, and as long as patients actively cooperate with the correct treatment, their life span can be prolonged. However, each patient’s physical condition, severity of the disease, treatment effect and other factors are not the same, although the same degree of disease, the survival period caused by individual differences, so it is difficult to give accurate clinical data. Because the survival period cannot be predicted, it depends on whether there is recurrence, whether there is distant metastasis, and individual response to treatment. Therefore, patients with middle and late stage colon cancer after surgery should undergo colonoscopy and related examinations regularly, and also pay attention to observing stools, and go to the hospital for regular rechecking. Check blood routine to see the degree of leukopenia caused by chemotherapy and whether there is any damage to liver function to prevent recurrence. If there is any discomfort, timely medical treatment, active cooperation, diagnosis and treatment under the guidance of professional doctors, can effectively extend life.