Amoxicillin capsule and Xiao Chai Hu Granules can be taken at the same time if you have a bacterial infection accompanied by a bad chill (fear of cold) and fever. Amoxicillin capsule is a western medicine. It is a β-lactam antibiotic and penicillin. It is used for upper and lower respiratory tract infections, genitourinary tract infections, soft tissue skin infections, acute simple gonorrhea, typhoid fever and leptospirosis. Adverse reactions are mainly gastrointestinal reactions, allergic reactions. Penicillin allergy and penicillin skin test positive patients are prohibited. Patients with infectious mononucleosis should be avoided. Xiao Chaihu Granules is a kind of Chinese patent medicine. It is composed of Chai Hu, Jiang Han Xia, Scutellaria baicalensis, Radix et Rhizoma Ginseng, Radix et Rhizoma Glycyrrhizae, Ginger and Jujube. It has the efficacy of relieving exterior heat and dispersing heat, evacuating the liver and harmonizing the stomach. It is used in treating exogenous diseases, with symptoms such as cold and heat (the body is hot and cold at the same time), bitter and fullness in the chest (the front and sides of the chest feel distended and uncomfortable), loss of appetite, upset and nausea, and bitter and dry mouth and throat. Adverse reactions and contraindications are not clear. It is not advisable to take tonic Chinese medicine at the same time while taking the drug. Not suitable for people with wind-cold flu. Amoxicillin capsule is mainly used for infections caused by sensitive bacteria, Xiao Chaihu Granules are mainly used for evil offending Shaoyang syndrome, symptoms such as malignant cold and fever. If the bacterial infection is accompanied by malignant cold and fever, the two medicines can be taken at the same time, and it is recommended that the Chinese and Western medicines be taken half an hour apart. If you need to use medication, it is recommended to use medication under the guidance of a doctor, not blindly self-medication to avoid adverse effects.