The type of antibiotics applied to urinary tract infections needs to be personalized and selected according to the patient’s condition, and in the clinic commonly used antibiotics such as quinolones and β-lactams, such as levofloxacin and cefuroxime. If there is an infection in the urinary system, the type, dosage and course of antibiotics need to be selected according to the location of the urinary tract infection and whether there are factors that complicate urinary sensation. Antibiotics that are sensitive to the causative organisms are usually chosen, and antibiotics that are effective against gram-negative bacilli are usually preferred based on clinical experience before there are any pathogenetic results. If symptoms do not improve after 3 days of treatment, the medication should be adjusted according to the drug sensitivity results. In case of simple cystitis, quinolones, cephalosporins and other antibiotics such as levofloxacin and cefuroxime can be applied. If pyelonephritis is combined with fever and other systemic symptoms, patients can choose penicillin or cephalosporin such as ampicillin, ceftriaxone and other treatment. All of the above medications should be used under the guidance of a doctor to avoid self-medication. Urinary system infection can also apply other antibiotics, if the patient has a urinary system infection, it is recommended to go to the regular hospital in a timely manner, under the guidance of the doctor standardized treatment.