You can use diuretics to eliminate swelling, or switch to other antihypertensive drugs for treatment. Nifedipine extended-release tablets are commonly used antihypertensive drugs in clinical practice, which are the representative of calcium antagonists. Swelling of the feet after taking nifedipine extended-release tablets is one of its common adverse reactions. The swelling of the lower limbs can be treated with diuretics to eliminate the swelling of the feet, and can also be treated by replacing antihypertensive drugs under the guidance of a doctor. Diuretics such as thiazides chlorothiazide and chlorthalidone can be used in combination, but blood potassium should be monitored when using diuretics, as hypokalemia can lead to digitalis drug toxicity. Diuretics are generally recommended to be taken in the morning. Other antihypertensive drugs are captopril, enalapril, propranolol, metoprolol, etc. Note that those who are allergic to the drug are prohibited. At the same time, attention should be paid to improve liver function, kidney function, cardiac ultrasound, BNP and other tests, or according to the situation to improve the lower limb ultrasound examination, to clarify whether there is any other causes of lower limb edema, if abnormalities are found, under the guidance of the doctor’s treatment. However, it should be noted that taking other drugs or replacing antihypertensive drugs should be carried out under the guidance of a specialized doctor, do not change drugs on your own, so as not to affect the development of the disease.