1. Calcium and vitamin D are the basic treatment for anti-osteoporosis, and are the “bricks” and “tiles” for building a tall building. The level of calcium does not depend on the level of blood calcium, but on the level of 24-hour urine calcium, the normal value is 100-300 mg. The level of vitamin D is >=25ng/ml. If liver and kidney function is good, no active vitamin D supplementation is needed. 2. Currently, anti-osteoporosis drugs are divided into pro-bone synthesis drugs and drugs that inhibit bone resorption. The former is parathyroid hormone, and the latter includes diphosphonate, estrogen, etc. In terms of the current situation, there is no drug that promotes bone synthesis and inhibits bone resorption at the same time. Because bone synthesis and bone resorption are inseparable, promoting or inhibiting the former must have the same promoting or inhibiting effect on the latter, and vice versa. The possibility of Chinese medicine as an auxiliary medicine exists. 3, at present, it is not advocated to use more than one kind of anti-osteoporosis drugs at the same time, if more than one kind of drugs that inhibit bone resorption are used at the same time, the side effects will be doubled because the mechanism of action is the same and the effect is not significantly increased. The simultaneous use of osteosynthesis-promoting drugs and bone-resorption-inhibiting drugs is also not recommended, because they interfere with each other and the effect is discounted. Sequential use of drugs can be tried. 4, how to choose pro-bone synthesis drugs and inhibit bone resorption drugs should be based on the patient’s specific personalized medication, the key is the risk of fracture in a certain period of time in the future. If the risk of fracture is high, then use pro-osteosynthesis drugs to rapidly increase bone mass. If the risk of fracture is not high, according to the principle of cost-benefit optimization, then choose drugs that inhibit bone resorption that improve bone mass more slowly. 5.Adherence to medication is the key to the success of anti-osteoporosis, and the rate of taking medication is more than 80% to be effective. 6.Sunbathing, exercise, and improving the environment to prevent falls are also important factors in anti-osteoporosis or putting a stop to fractures. 7.As a treatment provider, we should insist on following up and understanding the progress of osteoporosis treatment in the world, and make rationalized suggestions for patients.