Understanding Helicobacter pylori

The infection rate of H. pylori in China is very high, at a level of 50 to 60 percent, and it is transmitted by contact, mouth-to-mouth, fecal-oral route, and oral-gastric transmission. Today, we take you to know H. pylori, have a correct view of H. pylori. 1, H. pylori and what diseases are related to H. pylori with our gastric and duodenal ulcer disease, the most obvious is chronic gastritis, in addition, HP infection rate will increase with age, can cause superficial gastritis, erosive sinusitis and many focal atrophic gastritis, etc., in the second disease it causes is gastroduodenal ulcer. Most people are concerned about H. pylori and gastric cancer, H. pylori plays an important role in the development of gastric cancer is still relatively recognized, epidemiological researchers believe that gastric cancer is positively correlated with the high rate of H. pylori infection, that is, the incidence of H. pylori infection in areas with a high incidence of gastric cancer is also high. It is now proven that unexplained iron deficiency anemia and unexplained thrombocytopenic purpura, both of which are related to H. pylori. 2, the detection method of H. pylori detection methods are divided into two categories, one is invasive, through gastroscopy, take some gastric mucosa to detect, the other is non-invasive detection, commonly used is 13C and 14C urea breath test, as well as serum detection antibody, serum detection antibody is the simplest, draw a blood, check the antibody, but sometimes not very accurate. 3, H. pylori medication H. pylori treatment is now a quadruple drug, one is a proton pump inhibitor, the so-called omeprazole or lansoprazole, rabeprazole, another is a bismuth preparation, our country commonly used bismuth preparation is bismuth potassium raffinate, two antibiotics, these two antibiotics if penicillin is not allergic. Our recommended medication is amoxicillin one thousand milligrams twice a day, and the other recommended antibiotic is clarithromycin five hundred milligrams twice a day, taken orally. If you are allergic to amoxicillin, you can use metronidazole or you can use furazolidone and tetracycline, or you can use levofloxacin, five hundred milligrams once a day. Moxifloxacin 0.4, once a day is possible, the course of treatment is ten to fourteen days. All these antibiotics are taken orally, intravenous antibiotics for H. pylori have little effect. It is worth noting that after a course of treatment, all antibiotics and bismuth preparations should be stopped, in addition to stop the omeprazole proton pump inhibitors, after a month, at least a month later to review the breath test, or a gastroscopy test, H. pylori is negative, we can be sure that it has been eradicated. For an ordinary patient, H. pylori should be taken seriously, but it is not that scary. It is only one of the many factors in the development of gastric cancer, and it does not necessarily mean that if you have it, you will get gastric cancer. Only H. pylori, even after gastroscopy, the stomach is fine, and the inflammation of the gastric mucosa is not obvious, it is not necessary to treat it, but we should also pay attention to protection, that is to say, it is better to implement a meal sharing system with family members, not our traditional Chinese common meal. This is a very bad habit; mouth-to-mouth feeding of children is also a very bad habit, from the point of view of H. pylori, very easy to cause infection.