Poor glycemic control of diabetes, causing diabetic neuropathy, autonomic dysfunction, resulting in decreased excitability of peripheral nerves, and peripheral vascular atherosclerosis, vasospasm and narrowing of the peripheral blood vessels, poor peripheral circulation, the presence of long-term ischemia and hypoxia, which may be manifested in the form of cold feet. Diabetes causes cold feet, should promptly seek medical attention, and standardized treatment under the guidance of the doctor, to prevent further aggravation of microcirculation disorders, resulting in diabetic foot. The treatment of cold feet caused by diabetes is mainly to actively control blood sugar and nutrition of peripheral nerves, glucose-lowering drugs can choose insulin, metformin tablets, etc., and nutritive peripheral nerves drugs can choose methylcobalamin and so on. In addition to diabetes, other causes may also lead to cold feet, such as low environmental temperature, lower extremity blood circulation disorders or anemia. Diabetic patients with symptoms of cold feet are advised to consult a medical professional for diagnosis and treatment.